Frankly Speaking About Family Medicine

RSV Vaccine for Adults: Studies, Uses, and Patient Conversations - Frankly Speaking Ep 346

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-346
Overview: As we encounter more patients asking about the recent FDA approval of a new respiratory syncytial virus (RSV) vaccine for older adults, it’s crucial that we keep up to date. Join us as we review the supporting studies, indications, and precautions, giving you confidence in conversations with inquiring patients. 
Episode resource links:
https://www.fda.gov/news-events/press-announcements/fda-approves-first-respiratory-syncytial-virus-rsv-vaccine
Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

A Cool New Treatment for Hot Flashes? - Frankly Speaking Ep 345

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-345
Overview: In this episode, we discuss the findings of a recent Lancet publication on a novel neurokinin 3 (NK3) receptor antagonist for treating hot flashes. Tune in as we talk about how this nonhormonal treatment addresses menopausal hot flashes, the prescribing precautions issued by the FDA, and the implications for patients seeking your help with alleviating symptoms.
Episode resource links:
Lancet 2023; 401: 1091–102. doi.org/10.1016/ S0140-6736(23)00085-5
Am Fam Physician. 2023;108(1):28-39
Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

Risky Pain Management Choices in Patients with Dementia - Frankly Speaking Ep 344

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-344
Overview: Navigating the intricate landscape of pain management in older patients with dementia can be challenging. Join us as we explore strategies for mitigating pain, consider the equilibrium between opioid benefits and risks, and discuss where to start when tailoring management plans for patients with dementia and joint pain. Don’t miss this important conversation.
Episode resource links:
https://www.neurologylive.com/view/mortality-risk-significantly-increased-with-new-opioid-use-older-adults-dementia
https://www.practicalpainmanagement.com/resource-centers/opioid-prescribing-monitoring/risk-assessment-safe-opioid-prescribing-tools
Guest: Jillian Joseph, MPAS, PA-C Music Credit: Richard Onorato

Screens Off, Play On: How Parental Phone Use Shapes Kids’ Physical Activity - Frankly Speaking Ep 343

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-343
Overview: In this episode, we take a look at a study exploring the effects on children’s activity levels when their parents reduce smartphone use. Listen in as we discuss compelling findings that shed light on the connection, and come away with guidance on how to navigate the evolving digital landscape to promote healthier, more active lifestyles among children.
Episode resource links:
JAMA Pediatr. 2022 Aug; 176(8): 741–749BMJ Open. 2019 Jan 3;9(1):e023191. doi: 10.1136/bmjopen-2018-023191
Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

Beyond the Prescription Pad: Over-the-Counter Oral Contraceptive Gains FDA Approval - Frankly Speaking Ep 342

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-342
Overview: In July of 2023, the FDA made a monumental decision to approve Opill, marking the first time an oral contraceptive will be made available without a prescription. The inaugural over-the-counter oral contraceptive is a progesterone-only pill. Join us to discuss the underlying rationales driving this decision and the prospective implications it might have on medical practice as well as women’s health.
Episode resource links:
Biggs, AM, Ralph, L, Morris, N, Ehrenreich, K, Perritt, J, Kapp, N, Blanchard, K, White, K,  Barar, Grossman, RD.A cross-sectional survey of U.S. abortion patients’ interest in obtaining medication abortion over the counter, Contraception, Volume 109, 2022, Pages 25-31, ISSN 0010-7824,https://doi.org/10.1016/j.contraception.2022.01.010.
 
Chen, Q.J. Xiang, W.P. Zhang, D.K., Wang, R.P. Luo, Y.F. Kang, J.Z. Cheng, L.N. Efficacy and safety of a levonorgestrel enteric-coated tablet as an over-the-counter drug for emergency contraception: a Phase IV clinical trial, Human Reproduction, Volume 26, Issue 9, September 2011, Pages 2316–2321, https://doi.org/10.1093/humrep/der181
 
Raine, TR; Ricciotti, N; Sokoloff, A; Brown, B; Hummel, A; Harper, C. An Over-the-Counter Simulation Study of a Single-Tablet Emergency Contraceptive in Young Females. Obstetrics & Gynecology 119(4):p 772-779, April 2012. | DOI: 10.1097/AOG.0b013e31824c0aed
 
https://www.fda.gov/news-events/press-announcements/fda-approves-first-nonprescription-daily-oral-contraceptive
 
https://www.accessdata.fda.gov/drugsatfda_docs/nda/2023/017031Orig1s041SumR.pdf
Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Richard Onorato

Should We Personalize Our Approach to Treating Hypertension? - Frankly Speaking Ep 341

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-341
Overview: Listen in as we review a recent JAMA publication of a randomized controlled trial that quantified the benefits of a targeted approach to prescribing antihypertensive medications. Don’t miss this opportunity to keep your management of patients with hypertension up to date.
Episode resource links:
Sundström J, Lind L, Nawrouzi S, et al. Heterogeneity in blood pressure response to 4 antihypertensive drugs: a randomized clinical trial. JAMA. Published April 11, 2023. doi:10.1001/jama.2023.3322
Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

Get Up, Move, and Feel Better: Exploring Physical Activity’s Link to Reduced Suicidal Ideation - Frankly Speaking Ep 340

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-340
Overview: Depression and anxiety rates are escalating, with a 36% increase in suicide cases between 2018 and 2021, as reported by the CDC. This distressing trend can be attributed to various significant stressors that have arisen in recent times, such as pandemic-related illness and isolation. Medications alone are not as effective as when other modalities are incorporated into the treatment regime. Recent meta-analysis has revealed a strong correlation between engaging in physical activity and reducing suicidal ideation across all levels. Listen in as we discuss these findings and explore practical strategies for their implementation in your clinical practice.
Episode resource links:
Vancampfort, D., Hallgren, M., Firth, J., Rosenbaum, S., Schuch, F. B., Mugisha, J., Probst, M., Van Damme, T., Carvalho, A. F., & Stubbs, B. (2017). Physical activity and suicidal ideation: a systematic review and meta-analysis. Journal of Affective Disorders. https://doi.org/10.1016/j.jad.2017.08.070
https://www.healio.com/news/primary-care/20230403/metaanalysis-exe
Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Richard Onorato

CBD Use and Liver Injury: Practical Considerations for Primary Care - Frankly Speaking Ep 339

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-339
Overview: In this episode, we dive into a recent systematic review and meta-analysis confirming the association between cannabidiol (CBD) use and hepatotoxicity. Gain a deeper understanding of clinical applications and the delicate balance of risks and benefits when discussing CBD use with your patients.
Episode resource links:
Lo LA, Christiansen A, Eadie L, Strickland JC, Kim DD, Boivin M, Barr AM, MacCallum CA. Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis. J Intern Med. 2023 Mar 13. doi: 10.1111/joim.13627. Epub ahead of print. PMID: 36912195.
https://store.samhsa.gov/sites/default/files/pep22-06-04-003.pdf
Guest: Jillian Joseph, MPAS, PA-C Music Credit: Richard Onorato

Asthma May Induce Some Cancers—Can That Be Prevented? - Frankly Speaking Ep 338

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-338
Overview: Listen in as we explore the connection between asthma and cancer. We examine new Global Initiative for Asthma (GINA) guidelines and recent observational data correlating an asthma diagnosis with an increased cancer risk. Don't miss out on this essential discussion that will empower you with valuable knowledge for enhanced patient care.
Episode resource links:
Guo, Y, Bian, J, Chen, Z, et al. Cancer incidence after asthma diagnosis: Evidence from a large clinical research network in the United States. Cancer Med. 2023; 00: 1- 7. doi:10.1002/cam4.5875
GINA guidelines 2022: https://ginasthma.org/wp-content/uploads/2022/07/GINA-Main-Report-2022-FINAL-22-07-01-WMS.pdf
Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

When Is the Best Time to Take Blood Pressure Medications? - Frankly Speaking Ep 337

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-337
Overview: There has been uncertainty as to the best time for patients to take blood pressure medications. Tune in as we review the Treatment in Morning versus Evening (TIME) study, which assessed whether morning or evening dosing improves cardiovascular outcomes.
Episode resource links:
Mackenzie IS, Rogers A, Poulter NR, et al. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet. 2022;400(10361):1417-1425. 
Guest: Alan M. Ehrlich MD, FAAFP Music Credit: Richard Onorato